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The crash occurred in the westbound lanes near milepost 28.4 in Roxbury Township, NJSP Sgt. Philip Curry told Daily Voice.
A Kia hit the left guardrail, traveled back across the lanes and crashed into a Toyota before hitting the right guardrail and overturning around 5:15 p.m., Curry said.
The Kia driver was seriously injured, and the Toyota driver sustained minor injuries in the crash, authorities said.
The right and center lanes were shut down for about three hours, which caused heavy traffic delays, Curry said.
The cause of the crash remained under investigation.
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